Description
Product Characteristics:
Aliases: 4)-dienoyl-CoA isomerase antibody, 5)-Delta(2 antibody, Delta(3 5) Delta(2 4) dienoyl CoA isomerase antibody, Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial antibody, Delta(3 antibody, Delta3 5 delta2 4 dienoyl CoA isomerase antibody, Dienoyl CoA isomerase antibody, ECH 1 antibody, Ech1 antibody, ECH1_HUMAN antibody, Enoyl Coenzyme A hydratase 1 antibody, Enoyl Coenzyme A hydratase 1 peroxisomal antibody, HPXEL antibody, mitochondrial antibody, MS1034 antibody, Peroxisomal enoyl CoA hydratase 1 antibody, Peroxisomal enoyl coenzyme A hydratase like protein antibody
Target Information: This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq, Jul 2008]